- AC Hotel by Marriott Panama City
- Albrook Inn
- Aloft Panama
- American Trade Hotel
- Best Western Plus Panama Zen Hotel
- Bristol Panama, a Registry Collection Hotel
- Central Hotel Panama Casco Viejo
- Central Park Hotel & Casino
- Courtyard by Marriott Panama Metromall
- Courtyard by Marriott Panama Multiplaza Mall
- Covadonga
- Cresta Inn
- Decapolis Hotel Panama City
- Dreams Playa Bonita Panama
- Dumas Villas
- Eurohotel
- Exe Oriental Panamá
- Express Inn Pty Aeropuerto Internacional Panama
- Gamboa Rainforest Reserve
- Global Hotel Panama
- Grand International Hotel
- Hampton by Hilton Panama
- Hilton Garden Inn Panama City Downtown
- Hilton Panama
- Holiday Inn Panama Canal
- Holiday Inn Panama Distrito Financiero
- Hospedium Princess Hotel Panamá
- Hostal Gemar
- Hostal Loco Coco Loco
- Hotel 2 Mares
- Hotel Bahia Suites
- Hotel Bella Vista
- Hotel Benidorm Panama
- Hotel California Panama
- Hotel Caribe Panamá
- Hotel Casa Panama
- Hotel Coral Suites
- Hotel Costa Inn
- Hotel Discovery
- Hotel Doral
- Hotel El Panama by Faranda Grand
- Hotel Faranda Express Soloy and Casino
- Hotel Latino
- Hotel Lisboa
- Hotel Marbella
- Hotel Marparaiso
- Hotel Montreal
- Hotel Ojos del Rio
- Hotel Parador
- Hotel Pension Corona
- Hotel República
- Hotel Terranova
- Hotel Tower House Suites
- Hotel Via Espana
- Intercontinental Miramar Panama, An IHG Hotel
- JW Marriott Panama
- Las Americas Golden Tower Panama
- Las Clementinas
- Le Méridien Panama
- Marinn Place Financial District
- Marriott Executive Apartments Panama City, Finisterre
- Marriott Panama Hotel
- Megapolis Hotel Panama
- Metro Hotel Panama
- Monkey Lodge Panama
- Novotel Panama City
- Plaza Paitilla Inn
- Posada 1914
- Principe Hotel and suites
- Radisson Hotel Panama Canal
- Ramada Panama Centro via Argentina
- Ramada Plaza Panama Punta Pacifica
- Riande Aeropuerto Hotel Casino
- Riande Urban Hotel
- Riu Plaza Panama
- Sheraton Grand Panama
- Sortis Hotel, Spa & Casino, Autograph Collection
- Summit Rainforest & Golf Resort
- TRYP by Wyndham Panama Centro
- Tantalo Hotel
- The Balboa Inn
- The Beach House
- The Executive Hotel
- The Westin Panama
- Torres de Alba Hotel & Suites
- Toscana Inn Hotel
- Veneto Hotel & Casino
- Victoria Hotel and Suites Panama
- Villa Palma Boutique Hotel
- W Panama
- Waldorf Astoria Panama